ACTRISAVE(TM) is a blend of Oryza sativa (L.) and Opuntia cus indica (L.) extracts which supports from inside against skin disorders. Cactus flowers are traditionally used in folk medicine as a source of active flavonoids and black rice is recognized for its strong antioxidant compounds. The well-known antioxidant effect of anthocyanins contained in black rice used in combination with the hormonal balancing effect of cactus flower flavonoids (isorhamnetin and derivatives) can produce a synergistic protective effect in sebocytes and hair dermal papilla cells.